mitochondrial swellings การใช้
- These can lead to mitochondrial swelling and depolarization.
- In the initial parts of the dendrites, mitochondrial swelling and dilation can be seen.
- However, in electron microscopy relaxed myofibrils, as well as glycogen loss and mitochondrial swelling can be seen.
- The ultrastructural appearance of necrosis is quite different, the main features being mitochondrial swelling, plasma membrane breakdown and cellular disintegration.
- The first signs of degeneration seen after the removal of the bulb was mitochondrial swelling and then an increase in electron density in the cytoplasm.
- The hydrogen flux disrupts the mitochondrial membrane potential and results in mitochondrial swelling, outer membrane rupture, and the release of pro-apoptotic factors.
- Sustained activation for a longer period of time leads to further mitochondrial swelling, resulting in the release of cytochrome c, which initiates a cascade of cellular death.
- Apoptotic events such as membrane blebbing, phosphatidylserine flips ( exposure to extracellular space ), mitochondrial swelling, and microvesicle shedding are present, but cellular death does not occur.
- Instead, paraptosis displays a somewhat primitive cell death path, comparable to necrosis, including characteristic cytoplasmic vacuole formation and late mitochondrial swelling The number and size of vacuoles increases over time.